Only time will tell that how far heart doctors are convinced with the potency and safety profile of new anti-coagulants, so as to replace the older and effective warfarin medication. It is known that Pradaxa and Xarelto.
(prHWY.com) August 10, 2012 - Fontana, CA -- 10 August 2012, USA California (Acedrugstore.com): The advent of the new anti-coagulant drugs such as Pradaxa, Xarelto, etc in the clinical market has become a hot new topic of the whole pharma world, with health care professionals being skeptic about its utilization and safety profile.
Warfarin was the most preferred and widely used anticoagulants till date, that though associated with negative side effects was found to outweigh its benefits in treating people with heart complications.
The anti-coagulant medications that are currently available in the drug store include Boehringer Ingelheim's Pradaxa as well as Bayer and Johnson & Johnson's drug Xarelto. Whereas, another anticoagulant drug called Eliquis, a product of the Pfizer and Bristol-Myers Squibb is currently in its pipeline awaiting FDA's approval.
The major problem with respect to the use of the new medications and the vital difference between warfarin and tits counter drugs is the fact that the negative effects caused by warfarin can be swiftly reversed with the aid of an antidote; while, the same does not exist for the recent medications.
Hence, doctors are of a pessimistic view with regards to its recommendation to the general population and this has made it difficult for the drug makers to sell their product in market, which was previously thought to be an easy task.
Though the new drugs are found to posses bleeding a risk, which is regarded as a common aspect of every anti-coagulant medication, one of the positive points of the drugs with respect to warfarin is that they do not involve regular monitoring as does warfarin.
Pradaxa is found to increase the risk of bleeding in patients with poor kidney function in addition to unwanted interaction with other medications, thereby mitigating its effect.
Dr. Sanjay Kaul, a cardiologist claimed that if healthcare professionals make kidney function test mandatory prior to prescription of these drugs, then some of its negative aspects can be hindered.
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