A new research study showed that there exist a link between obesity and diabetes.
(prHWY.com) June 1, 2012 - Fontana, CA -- 1 June 2012, USA (Acedrugstore.com): A new research study showed that there exist a link between obesity and diabetes and this may prove to be of great significance in enduring new therapeutic approaches for targeting diabetes. The research carried out by the University of Michigan Health System shed light on glucagon, the hormone produced by the pancreas that has an opposite effect as that of insulin.
The study explored new clinical insights by changing the normal tracks of insulin and getting into details of glucagon and its effect, which lead to a significant intervention into its effectiveness in treating as well as preventing the high levels of blood sugar in diabetes.
Liangyou Rui, Senior author and associate professor at the University of Michigan Medical School said that many research have been carried out on insulin and its effect in lowering glucose levels. While on the other hand, only few clinical investigations have been carried out on the role of the other hormone produced by the pancreas (glucagon) in controlling the blood sugar levels in the body.
He also said that their study was unique and the first of its kind in history that showed a significant association of glucagon with obesity and its contribution to the escalating blood sugar levels found in the body.
The research claimed that NIK/NF-B2 pathway is the central to your rising blood sugar levels and this is responsible for abnormal activation of glucagon in case of obese individuals, while the hindrance of liver NIK was found to heal diabetic complication in overweight mice.
Insulin resistance is the main characteristic of type 2 diabetes and a common hypothesis states that the inflammation of fat and liver tissue causes resistance in insulin that ultimately results in elevation of blood glucose levels. There exists a possibility that increase in sugar level may have caused by glucagon due to the inflammation.
Further studies are suggested to provide a better clue into the activity of this hormone and its future aspect of production of anti-diabetic medicine
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