Platelets play a key role in both hemostasis and thrombosis

Platelets play a key role in both hemostasis and thrombosis. Accordingly, not only is accurate measurement of platelet function critical for identifying patients with platelet dysfunction or hyperfunction but it also is becoming increasingly importan

TX, TX (prHWY.com) March 6, 2013 - Texas, Mar 06, 2013 - Platelets play a key role in both hemostasis and thrombosis. Accordingly, not only is accurate measurement of platelet function critical for identifying patients with platelet dysfunction or hyperfunction but it also is becoming increasingly important for the monitoring of modern antiplatelet therapy.


The POPULAR trial put Plateletworks® on the short list of platelet function assays that actually work to catch non-responders to the anti-platelet drug Plavix® (clopidogrel) at higher risk for cardiovascular events. Plateletworks can be used anytime there are general concerns about the effect of drug therapies on platelet function. Turnaround is about 5--minutes using traditional agonists including ADP, collagen and arachidonic acid and a standard impedance cell counter. Plateletworks is much more cost-effective than other platelet function assays as well.

In about two minutes, monitor Platelet Count and real Platelet Aggregation or Inhibition at the point of care using traditional ADP, collagen or Arachidonic acid agonists. All that's needed is an impedance cell counter and Plateletworks.

* Platelet Aggregation

* Platelet Inhibition

* Platelet Count

* CBC

Platelet Function Screening -By directly monitoring the platelet's ability to form an aggregate, it's a direct measurement of the platelet's ability to contribute to a thrombus. Plateletworks can be used to monitor all mechanisms which affect platelet aggregation:

* Physiological conditions such as fibrinolytic damage to glycoprotein la

* Aspirin and ADP inhibitors (clopidogrel, ticlopene)

* Glycoprotein IIb/IIIa inhibitors (abciximab, eptifibatide, tirofiban)

* Plus Arachidonic Acid agonist is the only aspirin screening assay suitable for patients on both clopidogrel and aspirin

Plateletworks Point of Care Kits provide a complete hematology profile, including
a standard CBC with platelet count plus platelet aggregation. Aggregation testing is
based on performing a platelet count before and after intentional platelet activation, using either collagen, ADP or arachidonic acid as the agonist. The procedure is simple and no special sample preparation is required. A 1.0 cc whole blood sample is added to both a Baseline and an Agonist Reagent Tube. Both tubes are run on a standard impedance cell counter. Results are available in minutes. Testing can be performed at the patient site of care with excellent correlation to traditional
PRP aggregation assays.



Monitor anything affecting platelets

* Physiological conditions such as fibrinolytic damage to glycoprotein Ia
* Effects of pharmacologic preparations
* Aspirin and ADP inhibitors (clopidogrel,ticlopene, prasugrel)
* Glycoprotein IIb/IIIa inhibitors (abciximab, eptifibatide, tirofiban)

About the Author:

Platelet Function Screening - Helena Laboratories is a clinical laboratory instrument and reagent manufacturer. Our clients include major medical centers, small hospitals, large reference laboratories and small private doctor's laboratories.

Contact Details:

HELENA Laboratories
Beaumont, Texas,
USA

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